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EPOREX application fields and activities
What is mesotherapy?
Mesotherapy has recently been the fastest growing aesthetic treatment in Europe and USA. Developed by a French doctor in the 1950's, the theory behind mesotherapy is that certain conditions might be best treated by injecting small amounts of medicine directly into the problematic area. This avoids the problem of digestive tolerance associated with oral medications which require much larger doses. Mesotherapy can improve a wide range
of aesthetic conditions by introducing amino acids, vitamins and minerals beneath the skin. The natural, non-toxic, cosmetic ingredients are typically derived from herbs and vegetable extracts and work by reversing the physiology of the condition which translates into long-lasting results.
The new innovative Isophoresis technique with EPOREX
EPOREX is an optimised system of cutaneous transport on the basis of a large number of accredited studies and research, in particular the research in the field of physical mechanisms that increase the penetration and spread of active principles into the epidermis. EPOREX launches a new generation of transdermal delivery systems, bringing about the synergy of already known techniques such as Ionophoresis, Iontophoresis, and Electroporation, through an innovative method for "active" molecular transcutaneous transport that is called: "ISOPHORESIS".
EPOREX offers needle-free mesotherapy treatments without pain or bruising and so opens to the therapist a range of treatments which where previously reserved for medical practitioners.
EPOREX mesotherapy involves transferring small amounts of Medical Technology's powders and homeopathic formulations immediately beneath the surface of the skin using Isophoresis to break down the cellulite and to improve circulation and lymphatic and venous drainage. Each treatment takes about twenty to forty minutes non invasively without pain and down time since the patient may return to its normal activities immediately after the therapy. Treatment may be carried out immediately after an initial consultation: some individuals may require a course of 4 weeks, although a full treatment course takes 8 weeks. The treatment is long lasting and the results measurable. Superb results are achieved and those being treated look and feel better both during and after treatment. Overall, with a moderate amount of lifestyle change, mesotherapy can provide measurable improvements.
What is electroporation?
This methodology is employed in medical therapy by exploiting its invasive feature, leading to an increase in the permeability of the skin tissue. Electroporation of the skin occurs when, a transmembrane potential is generated within an epithelial cell structure. As a result, the lipid layer of the cell membrane is subjected to an alteration: the formation of the well known aqueous vessels, hence called "electropores". The creation of electropores occurs at a subsequent time, after the induction of the electric pulse, and takes only a few minutes, thus leading to a diffusive permeability of the molecules, even of high weight, that enables them to penetrate through the entire tissue 'targeted' by the electric pulse. The aqueous vessels will preserve themselves for a period directly proportional to the wave length of the pulse itself. This span ranges from few seconds to about ten minutes. This has been recently established by chemical-biological field researches, in the well known study on "vessels dedicated to transport of water into cells''. This study was awarded in the year 2003 with the Nobel prize for chemistry, which went to two eminent American researchers, Roderick MacKinnon and Peter Agre. In fact, thanks to this study, it was possible to discover the existence of molecular vessels which enable the cellular membrane to let in or out vital substances as water and salts (membrane proteins).
What is isophoresis?
The main difficulty for the liberation of substances through the human skin is the external layer, i.e. the corneal layer that is a tough barrier to the transport of substances; its lipid-corneocyte matrix has been the subject of studies regarding: variations of impedance of the dermis subject to impulse charges, and the consequent variation of its permeability; determination of the wave shapes useful for transport purposes; creation of a wave shape generator.
With ISOPHORESIS an attempt has been made to optimise the transport method to avoid the limits posed by techniques used in the past, i.e. the poor concentration of active principle, the limited depth reached in the tissues, the damage of the tissues due to the intense currents induced. For these reasons, the isophoretic method represents the avant-garde in skin treatments. New research has already been carried out in various countries with outstanding results representing the future of this new needle-free technique.
Ionization Chamber
The ionization chamber is a innovative structure inside the handpiece. In the chamber the osmotic and conductive processes of the substances gradually take place. A bottle of a conductive gel is mixed with the dehydrated powders (according to the protocols) immediately before the use.
The handpiece is structured in such a way that the armature of the ionization chamber is fixed and constantly in contact with the mixture and ensures a constancy of ionisation of the active principle for later transmission.


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